Antimicrobial Activity of Oxygen Active Gel against Porphyromonas gingivalis Contamination at the Implant-abutment Interface.
Bacterial contamination at the dental implant-abutment interface through microgaps can lead to peri-implant tissue infections, resulting in marginal bone loss and compromising the long-term success of dental implants. This in vitro study from Brazil, published in the Journal of Advances in Medicine and Medical Research, aims to evaluate the antimicrobial activity of blue®m oral gel against Porphyromonas gingivalis (Pg) at the implant-abutment interface (IAI) in three different types of implant-prosthetic connections.
Wang Hsing Han 1), Sabino Haroldo Ferrari Jr 1), Rafaela D. Parolina de Carvalho 2), Rogério Nagai 1), Alexandre Miyahira 1), Karina Cogo-Müller 2), Marcia Hiromi Tanaka 1), Debora Pallos 1) and Yeon Jung Kim 1)*
1) Department of Post-graduation in Implantology, School of Dentistry, University of Santo Amaro, São Paulo-SP, Brazil.
2) University of Campinas – UNICAMP, Campinas-SP, Brazil.
Abstract
Background: Bacterial contamination at the dental implant abutment interface through microgap may lead to peri-implant tissue infections resulting in marginal bone loss and affecting the long term success of implants.
Aims: The purpose of this In vitro study in vitro was to evaluate the antimicrobial activity of oxygen active gel (blue®m) against Porphyromonas gingivalis (Pg) at the implant-abutment interface (IAI) in three different types of implant-prosthetic connections.
Methodology: A total of 45 dental implants with three different types of connections were divided into three groups (n=15/each) according to filling product at the interface: Control (C) – unfilled, BlueM (BM) – oxygen active gel, Chlorhexidine (CX) – 2% chlorhexidine gel. They were incubated with a solution containing Pg for 5 days under anaerobic condition. Bacterial contamination at the interface were detected and quantificated by qPCR.
Results: All 45 implants showed contamination at the IAI by Pg after 5 days of incubation, independent of prosthetic connection type. EH type connections showed greater contamination by Pg compared to MT type connections (p=0.0098). No differences were observed among different types of connections in BM and CX groups.
Conclusion: The application of active oxygen gel promoted a reduction in P. gingivalis contamination in EH type connections at the IAI in vitro, but did not eliminate it completely.